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Anticorpii heterofili sunt primii anticorpi care apar în serul pacientilor care au contactat virusul Epstein-Barr, la 1- 3 săptămâni de la debutul simptomelor, în 85-95% de cazuri. Aceşti。

Diagnosticul de mononucleoză infecţioasă se stabileşte pe date clinice (febră, faringită, adenopatii, hepatosplenomegalie), aspectul frotiului de sânge periferic (limfomonocite。

The mononuclear spot test or monospot test, a form of the heterophile antibody test, is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. The test is specific for heterophile antibodies produced by the human immune system in response to EBV infection. Commercially available test kits are 70–92% sensitive and 96–100% specific, wi…

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